As the state’s most historic university, we’re rooted in tradition. But we’re also looking toward the future, providing you with the new skills and flexible learning methods you need to navigate an increasingly complex world.
USD’s beautiful 274-acre campus sits along the bluffs above the Missouri River in southeast South Dakota. From the historic beauty of Old Main to the cutting-edge technology housed in the Lee Medicine & Science Building, you’ll experience a mix of the traditional and contemporary on the University of South Dakota campus. Since its inception in 1862, USD has called the small, safe city of Vermillion home. As both grow in size and population, the campus and the city continue to enjoy a mutually beneficial relationship that helps foster innovation and creates exciting opportunities for both students and residents.